Development of gold nanoparticles stabilized by PLGA and PVA for application in photothermal therapy.

ABSTRACT:

Introduction

In today's world, cancer remains a major public health problem. Consequently, there has been a focused investigation of alternative therapeutic approaches to address this ongoing health concern. In this study, PLGA-gold nanomaterials were produced through various processes to determine whether these variations affected their structural integrity and, consequently, their physicochemical properties.

Methods

The PLGA-gold nanomaterials were produced through an oil-in-water (O/W) process (Formulation A) or a water-in-oil-in-water (W1/O/W2) process (Formulation B). The nanomaterials' physiscochemical properties were characterized by electron microscopy, dynamic light scattering, and UV-vis. Photothermal studies were performed using a 808 nm NIR laser and the PLGA-gol

SUBMITTER: Borges S 

PROVIDER: S-EPMC12916575 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature