Clinical determinants of agreement and discordance between stress SPECT and invasive coronary angiography.

ABSTRACT:

Background

Stress single-photon emission computed tomography (SPECT) myocardial perfusion imaging offers a non-invasive alternative for invasive coronary angiography (ICA) in diagnosing coronary artery disease (CAD), however often yields inconclusive results. This study aimed to characterize patterns of agreement and discordance between stress SPECT and ICA, and to evaluate potential risk stratification.

Methods

We retrospectively analyzed 915 patients with suspected CAD who underwent stress SPECT followed by ICA within three months (enrollment: 2019-2020). Clinical, demographic, and imaging data were extracted from medical records. Variables associated with diagnostic agreement were identified using univariate logistic regression. A predictive model combining SPECT results

SUBMITTER: Danon M 

PROVIDER: S-EPMC12916578 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature