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LncRNA TAF1A-AS1 regulates the progression in hepatocellular carcinoma by targeting miR-664b-3p/USP22 axis.


ABSTRACT:

SUBMITTER: Su H 

PROVIDER: S-EPMC12917072 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature

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LncRNA TAF1A-AS1 regulates the progression in hepatocellular carcinoma by targeting miR-664b-3p/USP22 axis.

Su Huizhao H   Yao Mei M   Hao Yuesong Y   Wang Zhiqian Z   Yuan Guandou G   He Songqing S  

Discover oncology 20260126 1


BACKGROUND: Long non-coding RNAs (lncRNAs) play an important regulatory role in tumorigenesis and progression. However the role of TAF1A-AS1 in hepatocellular carcinoma (HCC) remains unclear. Therefore, this study aimed to clarify the specific role of TAF1A-AS1 in regulating tumorigenesis and progression of HCC. METHODS: Quantitative real-time PCR (qRT-PCR) was used to determine the expression of TAF1A-AS1, miR-664b-3p and USP22 in tissue samples and cell lines. Functional assays, including Cell  ...[more]

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