Prognostic value of nine inflammatory biomarkers for 30-day mortality in critically ill elderly patients with osteoporotic hip fracture.

ABSTRACT: The study aimed to assess the predictive significance of various inflammatory biomarkers among critically ill elderly patients with osteoporotic hip fracture (OHF). The research identified critically ill elderly patients with OHF through the MIMIC-IV database. Nine systemic inflammatory indicators, formed by diverse combinations of neutrophils, lymphocytes, monocytes, and platelets, were evaluated for their associations with 30-day all-cause mortality after ICU admission. An examination of the receiver operating characteristic curve was conducted to determine the strongest predictive biomarker. In addition, the least absolute shrinkage and selection operator (LASSO) regression was applied to identify potential influencing factors. Furthermore, Cox proportional hazards regression and restri

SUBMITTER: Liu ZJ 

PROVIDER: S-EPMC12917132 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature