Factors Influencing HPV Vaccination Uptake in Adolescents: Evidence to Guide Clinical Practice.

ABSTRACT:

Background

Human papillomavirus (HPV) is a major contributor to several preventable cancers. Although the HPV vaccine is recognized by the Centers for Disease Control and Prevention (CDC) as safe and effective, uptake among U.S. adolescents remains below optimal levels. Disparities in vaccination rates are shaped by both individual characteristics and social determinants of health (SDOH).

Objective

To systematically review and synthesize the literature examining individual factors and social determinants of health associated with HPV vaccine initiation and completion among adolescents aged 9-18 years in the U.S.

Methods

A systematic search was conducted in accordance with PRISMA guidelines, yielding 37 eligible studies from an initial pool of 2092 articles. The STROBE

SUBMITTER: Mullin T 

PROVIDER: S-EPMC12917299 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature