Reproducibility and repeatability of the Myoton to quantify sclerotic chronic graft-versus-host disease.

ABSTRACT:

Abstract

There is an urgent need for validated tools to measure sclerotic cutaneous chronic graft-versus-host disease (scGVHD). We examined the interobserver reproducibility within a session and intraobserver repeatability between sessions of the Myoton device for quantifying skin sclerosis in 36 adults with scGVHD. The Myoton was used to measure oscillation frequency and relaxation time of soft tissues at 7 bilateral sites (14 anatomic sites) by 2 study personnel at 2 study sessions. Agreement was measured using mean pairwise absolute difference (MPD), and reliability was measured using intraclass correlation coefficient (ICC). For each of the 2 Myoton parameters, the overall interobserver MPD was <5% of the average overall values and the interobserver ICC was >0.90 between the 2

SUBMITTER: Farhadfar N 

PROVIDER: S-EPMC12917516 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature