Vitamin D levels and biomarkers of male fecundity: A study from the Danish National Birth Cohort.

ABSTRACT:

Background

Vitamin D is metabolised throughout the male reproductive system, suggesting a direct regulatory role of vitamin D in male reproduction.

Objectives

To investigate the association between plasma vitamin D levels at sperm ejaculation and during spermatogenesis and biomarkers of male fecundity in young men.

Materials and methods

From the Fetal Programming of Semen Quality cohort, Denmark, 2017-2019, 1047 young men provided a semen and a blood sample, and self-measured their testes volume at a clinical visit. Plasma levels of vitamin D (25(OH)D₃) and reproductive hormones were measured in the blood sample. Relative percentage differences in semen characteristics, testes volume and reproductive hormone levels were analysed according to measured vitami

SUBMITTER: Gaml-Sorensen A 

PROVIDER: S-EPMC12917574 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature