Global epidemiology of thyroid cancer: trends in incidence, mortality, and DALYs from 1990 to 2021.

ABSTRACT:

Objectives

This study provides the first comprehensive assessment of the global thyroid cancer burden from 1990 to 2021, focusing on incidence, mortality, and DALYs trends across 204 countries.

Methods

Using Global Burden of Disease (GBD) 2021 data, age-standardized rates (ASRs) and estimated annual percentage changes (EAPCs) were calculated. Associations with the Socio-demographic Index (SDI) were analyzed via linear regression.

Results

Globally, the age-standardized incidence rate increased from 2.06 to 2.91 per 100,000 (EAPC=1.25), with women accounting for 67 % of cases. Mortality showed a modest decline (EAPC=-0.23), but DALYs remained high (14.57 million in 2021). High-SDI regions, such as North America, accounted for 72 % of cases, reflecting intensive screenin

SUBMITTER: Lei W 

PROVIDER: S-EPMC12917600 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature