Guideline Adherence of Perioperative Antibiotics and Surgical Site Infections in Noncardiac Surgery.

ABSTRACT:

Importance

Despite nearly universal adherence to the Surgical Care Improvement Project (SCIP), surgical site infections (SSIs) persist. Compared with SCIP, which largely focuses on antibiotic timing, the Infectious Diseases Society of America (IDSA) guidelines provide a more comprehensive framework of antibiotic metrics, including procedure-specific antibiotic selection, weight-adjusted dosing, timing of the first dose, and appropriate redosing.

Objective

To assess whether nonadherence to each antibiotic administration metric of IDSA guidelines is associated with SSIs.

Design, setting, and participants

In this nationwide, multicenter, cross-sectional study, patients aged 18 years or older who underwent noncardiac surgeries involving a skin incision between January 1,

SUBMITTER: Bardia A 

PROVIDER: S-EPMC12917684 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature