Effects of an antimicrobial peptide on transport- and novel environment-induced stress in British Shorthair cats.

ABSTRACT: Antimicrobial peptides (AMPs) are natural short peptides with known immunomodulatory and anti-inflammatory properties. Their application in feline stress management have not been widely studied. This study aimed to evaluate the effects of dietary AMPs derived from Saccharomyces cerevisiae on cats exposed to transportation and novel environment. Twelve cats were randomly allocated to a control group or a group fed with AMPs. After pre-feeding for 2 weeks, all cats underwent a two-hour transportation and were subsequently housed individually in novel environment for 1 week. Behavioral observations, biochemical assays, gut microbiota analysis, transcriptomics, and metabolomics were performed. AMPs supplementation significantly increased nighttime sleep duration, reduced activity on tra

SUBMITTER: Chen S 

PROVIDER: S-EPMC12917902 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature