Ventilator settings for fiberoptic bronchoscopy during mechanical ventilation: a randomized adjudicator-blinded controlled trial VentSetFib.

ABSTRACT:

Background

During bronchoscopy in mechanically ventilated patients, bronchoscope insertion markedly increases airway resistance, elevating peak airway pressure and reducing delivered tidal volume. We sought to determine whether specific ventilator settings (assist volume-controlled with reduced inspiratory flow and tidal volume) lower serious adverse events during flexible fiberoptic bronchoscopy compared with conventional ventilator settings.

Methods

Single-center randomized adjudicator-blinded controlled trial in intubated adult patients undergoing fiberoptic bronchoscopy. Patients were assigned (1:1) to bronchoscopy-optimized settings (inspiratory flow ≤ 25L/min, tidal volume = 5mL/Kg, 1s ≤ inspiratory time ≤ 1.3s, respiratory frequency = 16 breaths/min, positive end-expi

SUBMITTER: Lemyze M 

PROVIDER: S-EPMC12918189 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature