A novel inflammation-nutrition risk score (INRS) and its related nomogram model to predict radiological bronchiectasis in patients after tuberculosis infection in Wuhan, China.

ABSTRACT:

Background

Tuberculosis infection (TBI) is a significant cause of bronchiectasis (BE). Identifying risk factors for radiological BE (RBE) could enhance the early detection of high-risk individuals following TB infection. This study aimed to develop and validate a novel Inflammation-Nutrition Risk Score (INRS) and a corresponding nomogram model to predict the risk of RBE after TBI.

Patients and methods

We enrolled 2,210 post-TBI patients from two medical centres. Data from 1,825 patients at Wuhan Jinyintan Hospital were used to develop the INRS and the RBE nomogram. An independent cohort of 385 patients from Wuhan Union Hospital served as an external validation set.

Results

The INRS was derived from four parameters: PNI, HALP score, Lg(SII) and CAR. Multivariate analys

SUBMITTER: Yu Q 

PROVIDER: S-EPMC12918364 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature