Development and validation of a neural network survival prediction model for ischemic heart disease.

ABSTRACT:

Background

Current risk prediction models for ischemic heart disease in clinical use are relatively simple and use a limited collection of well-known risk factors. Using machine learning to integrate a broader panel of features from electronic health records (EHRs) may improve post-angiography prognostication.

Methods

This retrospective model development and validation study was based on Danish EHR data. Icelandic EHR data were used for external test. Patients with a coronary angiography-confirmed diagnosis of coronary atherosclerosis between 2006 and 2016 were included for model development (n = 39,746). Time to all-cause mortality, the prediction target, was tracked until 2019, or up to 5 years, whichever came first. To model time-to-event data and deal with censoring, neu

SUBMITTER: Holm PC 

PROVIDER: S-EPMC12918636 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature