Five-year histological evaluation of paclitaxel-eluting stent for an infrapopliteal lesion: a case report.

ABSTRACT:

Background

The long-term vascular response to paclitaxel-eluting stents (PESs) in infrapopliteal (IP) lesions remains histologically uncharacterized.

Case summary

A 78-year-old woman with chronic limb-threatening ischaemia underwent implantation of two overlapping paclitaxel-eluting stents from the tibioperoneal trunk to the peroneal artery for an ischaemic ulcer. Multimodality follow-up imaging was obtained at both 3 and 5 years, including optical frequency domain imaging (OFDI) and angioscopy performed immediately before amputation. At 3 years, OFDI and angioscopy demonstrated uncovered struts with adherent thrombus. At 5 years, OFDI and angioscopy showed mature neointima over the proximal and distal segments but persistent fibrin-coated, uncovered struts within the 40-mm

SUBMITTER: Hata Y 

PROVIDER: S-EPMC12919362 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature