Preprocedural Left Atrial Strain as a Predictor of Long-Term Outcomes Following Mitral Valve Interventions in Rheumatic Severe Mitral Stenosis.

ABSTRACT:

Background

This study explores whether preprocedural left atrial (LA) strain predicts outcomes in individuals with rheumatic, severe mitral stenosis undergoing mitral valve (MV) interventions.

Methods

Data were from the MASTER (Multicenter Mitral Stenosis with Rheumatic Etiology) registry, including patients with severe mitral stenosis who underwent percutaneous mitral valvuloplasty or MV replacement. Participants with moderate or greater dysfunction of other valves or missing strain data were excluded. The primary outcome was a composite of all-cause mortality and heart failure hospitalization. Decreased LA reservoir strain was defined as <12.2%, determined through receiver operating characteristic analysis.

Results

Among 609 individuals (mean age 57.4±12.1 years; 73

SUBMITTER: Yoon SG 

PROVIDER: S-EPMC12919483 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature