Heart Failure Risk in Patients With Systemic Autoimmune Inflammatory Diseases.

ABSTRACT:

Background

Cardiac disease, including heart failure (HF), is a significant cause of morbidity and mortality for patients with systemic autoimmune inflammatory diseases (SAIDs). We sought to describe HF risk among patients with SAIDs and to investigate associations between cardiovascular drug use and incident HF.

Methods

We conducted a retrospective cohort study of electronic health records of 182 795 adult patients with SAIDs including systemic sclerosis, systemic lupus erythematosus, rheumatoid arthritis, psoriatic arthritis, inflammatory bowel disease, and HIV from 2000 to 2020 and track their risks of new-onset incident HF in a large multidisciplinary health care institution.

Results

Systemic sclerosis (adjusted hazard ratio [aHR], 2.81 [95% CI, 2.57-3.08]; P

SUBMITTER: Zagouras AA 

PROVIDER: S-EPMC12919521 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature