The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation.

ABSTRACT:

Background

Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.

Objectives

To elucidate the ontogeny, organization, and immunohistological features of human penile innervation in fetal and adult specimens, primarily focusing on the frenular delta, sensory corpuscles, and related structures to address gaps in anatomical knowledge and inform surgical practices.

Materials and methods

Formalin-fixed, paraffin-embedded tissues from 30 fetal (8-24 weeks) and 14 adult cadaveric penile specimens were analyzed. Routine histological stains and immunohistochemical ma

SUBMITTER: Cepeda-Emiliani A 

PROVIDER: S-EPMC12919687 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature