Cardiac findings in infants with in utero exposure to Zika virus - a follow up longitudinal study.

ABSTRACT:

Background

Zika virus (ZIKV) is primarily known for its impact on the fetal central nervous system potentially leading to Congenital Zika Syndrome (CZS). Emerging evidence suggests ZIKV may also affect cardiac development. We conducted a follow-up study evaluating cardiologic findings in infants from ZIKV-exposed mothers.

Methods

Infants born to mothers with PCR-confirmed ZIKV infection during pregnancy and/or who had positive ZIKV PCR results at birth received echocardiograms in the first year of life. Repeat imaging within 12 months was requested for infants with identified abnormalities. Frequencies of cardiovascular (CV) abnormalities were evaluated using Pearson χ2 test, Fisher's exact test, and descriptive statistics. Predictors of CV abnormalities were assessed using

SUBMITTER: Dang BN 

PROVIDER: S-EPMC12919927 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature