Association between glucagon and stroke in patients with type 2 diabetes.

ABSTRACT:

Objective

This study aimed to investigate the association between fasting glucagon levels and the risk of comorbid stroke in hospitalized patients with type 2 diabetes mellitus (T2DM).

Methods

This study included 1,745 T2DM patients hospitalized at Tianjin Medical University General Hospital from September 1, 2022, to September 30, 2025. Patients were divided into a T2DM group and a T2DM with stroke group based on the presence of stroke. Fasting glucagon levels and other clinical data were collected. Binary logistic regression models were used to analyze the relationship between fasting glucagon and stroke risk.

Results

Among female T2DM patients, fasting glucagon levels were significantly higher in the T2DM with stroke group compared to the T2DM group (13.38 vs 11.56

SUBMITTER: Kong L 

PROVIDER: S-EPMC12920052 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature