Association between the systemic immune-inflammation index and prognosis in patients with stroke: a meta-analysis of cohort studies.

ABSTRACT:

Introduction

The systemic immune-inflammation index (SII) is a newly recognized biomarker of inflammation. Although several studies have suggested that SII may aid in diagnosis of stroke and in predicting treatment outcomes, the findings remain inconsistent, and its relationship with clinical prognosis is still unclear. Therefore, we conducted a comprehensive systematic review and meta-analysis to explore the relationship between SII and clinical outcomes in patients with stroke.

Methods

We systematically searched four databases (PubMed, Embase, Cochrane Library, and Web of Science). The study adhered strictly to PRISMA guidelines. We assessed the risk of bias across the included studies using the Newcastle-Ottawa Scale. Key outcome indicators included poor functional outcom

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC12920226 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature