Cryoballoon Ablation for Persistent Atrial Fibrillation in Japan: Cryo Global Registry 12-Months Results.

ABSTRACT:

Background

Atrial fibrillation (AF) prevalence has increased with Japan's aging population. Data on cryoballoon ablation (CBA) for persistent AF (PsAF) in Japan is limited. This study reports CBA clinical outcomes in PsAF patients in Japan from the prospective Cryo Global Registry.

Methods

Data was analyzed from 60 Japanese centers with 1226 PsAF patients that underwent CBA. The primary endpoints were serious adverse events and freedom from atrial arrhythmia (AA) recurrence, at 12 months. The effect of ablation strategy (pulmonary vein isolation [PVI] or PVI with additional ablations [PVI+]) was evaluated. Quality-of-life (QoL) was measured by EQ-5D-3L questionnaire.

Results

The patient mean age was 68 ± 10 years and 29.0% were female. The overall 12-months Kaplan-Mei

SUBMITTER: Fukunaga H 

PROVIDER: S-EPMC12920677 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature