Preoperative Prediction of Non-functional Pituitary Neuroendocrine Tumors and Posterior Pituitary Tumors Based on MRI Radiomic Features.

ABSTRACT: Compared to non-functional pituitary neuroendocrine tumors (NF-PitNETs), posterior pituitary tumors (PPTs) require more intraoperative protection of the pituitary stalk and hypothalamus, and their perioperative management is more complex than NF-PitNETs. However, they are difficult to be distinguished via magnetic resonance images (MRI) before operation. Based on clinical features and radiological signature extracted from MRI, this study aims to establish a model for distinguishing NF-PitNETs and PPTs. Preoperative MRI of 110 patients with NF-PitNETs and 55 patients with PPTs were retrospectively obtained. Patients were randomly assigned to the training (n = 110) and validation (n = 55) cohorts in a 2:1 ratio. The lest absolute shrinkage and selection operator (LASSO) algorithm was applied

SUBMITTER: Jin S 

PROVIDER: S-EPMC12920986 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature