Single step nanosecond laser structuring for cost effective functional titanium surfaces with topography driven preosteoblast adhesion.

ABSTRACT: Early bone formation around implants depends on both the chemical composition and the micro-, nanoscale architecture of the implant surface. Nanoscale modifications can accelerate osseointegration, and laser processing offers a versatile method of creating such features. In this study, titanium substrates were modified using a single-step nanosecond laser treatment at two energy regimes (1.95 mJ/pulse for P_0.5; 4.00 mJ/pulse for P_0.4). The resulting surfaces were characterized by SEM, EDS, XRD, Raman spectroscopy, ToF-SIMS, contact angle, and topography measurements, with biological assessment performed using a mouse preosteoblast cell line. Analyses revealed various titanium oxo clusters (TiO₃^-, TiO₂^-, TiO^-) and moderate oxidation l

SUBMITTER: Barylyak A 

PROVIDER: S-EPMC12921291 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature