Perioperative outcomes in primary neonatal pullthrough versus pullthrough in older children with Hirschsprung disease: a systematic review and meta-analysis.

ABSTRACT: Primary pullthrough for Hirschsprung disease is the current standard in most uncomplicated standard segment disease. In this review and meta-analysis, we aimed to compare perioperative outcomes and functional outcomes for pullthrough done in the neonatal period compared to that in older age. PubMed, Medline, Embase, CINAHL, SCOPUS, and Web of Science were searched for relevant publications in English from inception to June 29, 2024. Twenty studies were included in the qualitative analysis with a total 3197 patients matching the review criteria. All included studies were observational in nature, with 1 prospective cohort study, 13 retrospective cohort studies, and 6 case series. Findings suggested primary pullthrough beyond 1 month of age was superior in most outcomes, including: shorter po

SUBMITTER: Alshahwani N 

PROVIDER: S-EPMC12921332 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature