A transitional desmosome/tonofibril network may relay mechanical strain to epidermal nerve terminals with high fidelity and sensitivity in the Cuban crocodile (<i>Crocodylus rhombifer)</i>: an ultrastructural study.

ABSTRACT:

Background

Crocodilians are well endowed with multiple cutaneous receptors and specializations, such as integumentary sensory organs (ISOs), which provide formidable mechanical sensitivity despite their protected shield. We investigated the free intraepidermal nerve terminals, focusing on the desmosomes, transitional desmosomes (TDs), corneodesmosomes (CD), and the tonofibril (TF) network that potentially act as force transducers to activate the mechanoreceptors.

Material and methods

Two Cuban crocodiles (Crocodylus rhombifer) were analyzed using light and transmission electron microscopy (TEM) after glutaraldehyde fixation and decalcification.

Results

Discoid nerve terminals were richly enclosed by an epidermal force-transmitting system (e.g., pressure and vib

SUBMITTER: Melkersson KG 

PROVIDER: S-EPMC12921410 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature