³¹P-MRS of the Human Heart at 7 T With an Integrated Whole-Body ³¹P Radiofrequency Transmit Coil.

ABSTRACT: Phosphorus-31 magnetic resonance spectroscopy (³¹P-MRS) can be used to characterize the steady-state in vivo myocardial energy status via the phosphocreatine (PCr) over adenosine triphosphate (ATP) tissue concentration ratio. Although used in many studies, this modality suffers from low sensitivity and poor measurement precision. This work reports on the acquisition of ³¹P-MR spectra of the in vivo human heart using a 7 T MR system equipped with an integrated whole-body RF transmit coil for ³¹P spin excitation. Eight volunteers (male/female, n = 4/4) underwent ³¹P-MRS at 7 T twice, using a low-flip angle, short-repetition time 3D ³¹P-MR spectroscopic imaging sequence with a 20-mm isotropic resolution and a 21-min acquisition time. A 16

SUBMITTER: Gosselink MWJM 

PROVIDER: S-EPMC12921427 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature