Multidisciplinary management of bronchoesophageal fistula using adipose-derived stromal vascular fraction and platelet-rich plasma.

ABSTRACT:

Background and aims

Bronchoesophageal fistula (BEF) is a rare but life-threatening adverse event following surgery. Fistulas result in respiratory adverse events, often requiring surgical repair, which is a high-risk procedure. Therefore, minimally invasive alternatives are needed. We aimed to use adipose-derived stromal vascular fraction (SVF) to treat BEFs.

Methods

We present 2 BEF cases after minimally invasive esophagectomy and gastric conduit reconstruction. During the procedure, SVF was isolated and platelet-rich plasma (PRP) obtained. In 1 case with a tracheaesophageal fistula, simultaneous bronchoscopy and endoscopy were performed to localize and treat the fistula; in the second case, only gastroscopy was performed to treat a fistula from the esophagus to the right u

SUBMITTER: van Dongen JA 

PROVIDER: S-EPMC12921678 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature