Comparative effects of transcranial direct and alternating current stimulation combined with cognitive-motor dual-task training on functional and cognitive recovery in stroke survivors.

ABSTRACT:

Aim

This study aimed to determine whether dual-target anodal transcranial direct current stimulation (tDCS) or transcranial alternating current stimulation (tACS) applied over the primary motor cortex (M1) and left dorsolateral prefrontal cortex (DLPFC), when combined with cognitive-motor dual-task training (CMDT), could enhance cognitive, physical, and mood outcomes in stroke survivors.

Methods

A single-blind, three-arm randomized controlled trial was conducted involving 72 stroke survivors. Participants were randomized to receive 15 sessions of dual-site (M1 + DLPFC) anodal tDCS, tACS, or sham stimulation, all administered concurrently with CMDT. Primary outcomes included cognitive performance (Visual Cognitive Assessment Test, VCAT) and physical function (Fugl-Meyer Lower

SUBMITTER: Fu Y 

PROVIDER: S-EPMC12921704 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature