Pharmacotherapy for Alcohol Craving Reduction: Efficacy of Short-Term Treatments in Alcohol Use Disorder.

ABSTRACT:

Background

Alcohol Use Disorder (AUD) is a major contributor to global morbidity, mortality, and socioeconomic burden. Cravings, defined as intense urges to consume alcohol, play a central role in relapse and are recognized as a diagnostic criterion in DSM-5. Pharmacological strategies targeting cravings may offer immediate or short-term relief, complementing existing long-term approaches. However, evidence on short-term (up to approximately three months) anti-craving interventions remains fragmented.

Objective

To systematically review randomized, double-blind, placebo-controlled trials (RCTs) assessing the short-term effects of pharmacological treatments on cue-induced alcohol cravings.

Methods

A systematic search was conducted in PubMed and PsycINFO using terms rela

SUBMITTER: Cheibub David Marin M 

PROVIDER: S-EPMC12921795 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature