Diagnostic Performance of Angiography-Derived Quantitative Flow Ratio: A Systematic Review and Meta-Analysis.

ABSTRACT: Background: Quantitative flow ratio (QFR) is a novel technology to assess the functional significance of coronary stenoses based on standard coronary angiography, which can be alternatives to invasive fractional flow reserve (FFR) assessment. However, the evidence is limited to single-center studies and small sample sizes. This study systematically determined the diagnostic performance of QFR to diagnose functionally significant stenosis with FFR as the reference standard. Methods: A systematic review and meta-analysis of studies assessing the diagnostic performance of angiography-derived QFR systems were performed. All relevant studies from six literature databases were searched and screened according to the inclusion and exclusion criteria. The pooled sensitivity, specifici

SUBMITTER: Huang G 

PROVIDER: S-EPMC12922042 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature