Tuning and clinical application of large language models in Traditional Chinese Medicine: scoping review.

ABSTRACT:

Background and objective

Large Language Models (LLMs) show significant potential in healthcare, but their application in Traditional Chinese Medicine (TCM) lacks systematic evaluation. This study aims to comprehensively review LLMs tuning techniques, data construction strategies, evaluation methods, and application scenarios in TCM clinical practice.

Methods

A scoping review following PRISMA-ScR guidelines was conducted. Researchers systematically searched seven databases for relevant studies published between database inception to May 2025. The analysis focused on identifying model characteristics, tuning techniques, data sources, evaluation methods, application domains and performance limitations to assess the current state and future directions of TCM-oriented LLMs.

Re

SUBMITTER: Han C 

PROVIDER: S-EPMC12922203 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature