Dataset Information
Differences in biochemical metabolism and cognitive function between bipolar I and bipolar II disorder.
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ABSTRACT:
SUBMITTER: Zhang R
PROVIDER: S-EPMC12922299 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature
Publications
Differences in biochemical metabolism and cognitive function between bipolar I and bipolar II disorder.
BMC psychiatry 20260202 1
BACKGROUND: This study aimed to characterise neurometabolic differences between bipolar disorder I (BD-I) and bipolar disorder II (BD-II), and to examine their associations with cognitive function. METHODS: A total of 50 patients diagnosed with BD-I, 80 patients with BD-II, and 50 healthy controls (HCs) were recruited for this study. Metabolite concentrations—specifically N-acetylaspartate (NAA) and choline-containing compounds (Cho)—were measured in the prefrontal white matter (PWM), anterior c ...[more]