Dataset Information
The impact of chronic and acute sleep deprivation on key Alzheimer's disease biomarkers: a systematic review and meta-analysis.
Ontology highlight
ABSTRACT:
SUBMITTER: Gosch Berton G
PROVIDER: S-EPMC12922396 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature
Publications
The impact of chronic and acute sleep deprivation on key Alzheimer's disease biomarkers: a systematic review and meta-analysis.
Fluids and barriers of the CNS 20260219 1
BACKGROUND: Sleep disruption is recognized as a risk factor for Alzheimer’s disease (AD). Both chronic and acute sleep deprivation (SD) may increase cerebrospinal fluid (CSF) levels of amyloid-beta (Aβ) and tau, potentially complicating early AD diagnoses. Some studies also suggest an inverse relationship in plasma biomarker levels, although these effects remain poorly characterized. METHODS: We conducted a systematic review and meta-analysis to examine whether SD elevates CSF concentrations of ...[more]