Multiparametric MRI for Predicting Renal Function Deterioration and Chronic Kidney Disease Development in Patients Undergoing Nephrectomy for Renal Masses: A Pilot Study.

ABSTRACT:

Background

Patients with solid renal masses (SRMs) are at risk of chronic kidney disease (CKD) after surgical resection without a reliable pre-operative predictor.

Purpose

To investigate whether pre-operative multiparametric MRI (mpMRI) can predict CKD development and progression to stage 3 CKD.

Study type

Prospective.

Population

Forty-three participants (female = 13, mean age: 59 ± 12 years) undergoing nephrectomy for SRM.

Field strength/sequence

1.5 T, diffusion-weighted echo-planar imaging (DWI) using nine b-values (0-800 s/mm²), T₁-mapping using variable flip angle, multi-echo gradient-echo blood-oxygen-level-dependent (BOLD), and dynamic-contrast-enhanced MRI (DCE-MRI) using 3D T₁-weighted gradient-echo.

Assessmen

SUBMITTER: Liu MM 

PROVIDER: S-EPMC12922647 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature