Emergence of satellite DNAs suggests centromeric repositioning as a driver of karyotypic variation of the freshwater darter characines (Apareiodon affinis).

ABSTRACT: Repetitive DNA sequences actively contribute to karyotype diversification by accumulating mutations, exhibiting susceptibility to DNA double-strand breaks that promote chromosomal rearrangements, and reshuffling within centromeric heterochromatin, among other processes. Parodontidae shows a conserved diploid number of 54, with predominantly metacentric and submetacentric chromosomes. Apareiodon affinis, from the Lower Paraná River, was described with three karyomorphs due to interpopulation structural variation, characterized by four to sixteen acrocentric chromosomes. However, the mechanisms driving chromosomal variation and the contribution of satellite DNA to these processes remain poorly understood. In this study, we characterized the A. affinis satellitome to assess the role of satell

SUBMITTER: Ribas MS 

PROVIDER: S-EPMC12923391 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature