The research landscape and future of targeting super-enhancers for cancer therapy: a bibliometric analysis.

ABSTRACT:

Background

Super-enhancers are specialized transcriptional regulatory elements pivotal for establishing and maintaining cell identity. Since their identification in 2013, SEs have garnered considerable attention as promising therapeutic targets in oncology. However, despite substantial progress, the molecular mechanisms and translational potential of SE-targeted strategies are not fully systematized, necessitating a comprehensive bibliometric analysis to map the intellectual landscape and guide future research.

Methods

We conducted a bibliometric analysis of 928 publications (2013-2024) from the Web of Science Core Collection using VOSviewer, CiteSpace, and R. The study employed co-occurrence, co-citation and cluster analysis to profile the research landscape, identifying le

SUBMITTER: Sun W 

PROVIDER: S-EPMC12923725 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature