Characterizing the co-occurrence of alcohol experimentation and suicidal thoughts and behaviors in early adolescence.

ABSTRACT: This study aims to investigate the roles of decision-making processes and genetics in the co-occurrence of alcohol use and suicidal thoughts/behaviors (STB) in adolescence. We used data from the ABCD^® study (abcdstudy.org) and included behavioral (computerized tasks, self-report questionnaires) and genetic (polygenic scores [PGS]) measures related to cognitive (executive functions) and affective (delay-discounting, risk-taking, impulsivity) processes involved in decision-making. First, we evaluated the latent structure of decision-making in the full sample (N = 11,868) using a split-half exploratory and confirmatory factor analysis. Second, we evaluated the association between alcohol experimentation ( > 1 sip) and STB in three genetically-defined ancestry groups: European (EUR,

SUBMITTER: Lannoy S 

PROVIDER: S-EPMC12923825 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature