Dataset Information
Whole-cell modeling predicts alternative proteome allocation strategies in the archaeon Methanococcus maripaludis.
Ontology highlight
ABSTRACT:
SUBMITTER: Kasem GS
PROVIDER: S-EPMC12923902 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature
Publications
Whole-cell modeling predicts alternative proteome allocation strategies in the archaeon Methanococcus maripaludis.
Scientific reports 20260219 1
The archaeon Methanococcus maripaludis (M. maripaludis) is a model organism for studying archaeal physiology and energy conservation in the hydrogenotrophic methanogenesis pathway. M. maripaludis has a distinct proteome allocation strategy, in which ribosomal proteome allocations do not change with growth rates. Here, we developed a proteome-constrained metabolic model that can explain this different proteome allocation strategy. First, we used multiple bioinformatics databases to compile inform ...[more]
