Obstructive sleep apnea in adults with Down syndrome: body composition, metabolic profile and cognitive status.

ABSTRACT:

Context

Down Syndrome (DS) is the main genetic cause of Intellectual Disability (ID) and is characterized by the presence of several medical comorbidities. Among these, Obstructive Sleep Apnea (OSA) stands out, with a prevalence much higher than that of the general population. The clinical impact of OSA in subjects without DS described in the literature includes increased cardiovascular, metabolic and neurocognitive risk. However, among the adult population with DS, these associations are poorly described.

Objectives

To evaluate the presence and characterize OSA in adults with DS and its association with body composition, metabolic profile, functional and cognitive performance.

Methods

This cross-sectional study included 34 persons with DS aged 18 years or over. The m

SUBMITTER: Ivanovic LF 

PROVIDER: S-EPMC12924187 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature