Invasive ventilation and mortality in critically ill nonagenarians: a retrospective cohort study.

ABSTRACT:

Background

ICU admissions among very old patients are increasing. Invasive ventilation (IV) is common, but its benefit in patients aged ≥ 90 years is uncertain given high mortality and ethical concerns.

Methods

This retrospective cohort study analysed all consecutive ICU patients aged ≥ 90 years admitted between 2008 and 2023 at a tertiary care centre in Germany. Demographic, clinical, and outcome data were extracted from electronic health records. Multivariable logistic regression was used to identify predictors of hospital mortality, while Kaplan-Meier survival analysis and Cox proportional hazards regression were used to assess predictors of 1-year mortality.

Results

Of 113,950 patients, 1422 (1.25%) aged ≥ 90 years were identified (median 92 years, IQR 91-94; 66%

SUBMITTER: Haar M 

PROVIDER: S-EPMC12924332 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature