Antipsychotic treatment patterns and cardiometabolic medicine use: current real-world evidence.

ABSTRACT:

Aims

Off-label use of antipsychotics, often at low doses, is increasing. Exploring the link between individual antipsychotic treatment patterns, including low-dose continuous use, and cardiometabolic health is crucial to prevent long-term morbidity and mortality. The current retrospective study examined the prevalence of cardiometabolic medicine use among antipsychotic-users, and its association with their past antipsychotic treatment patterns.

Methods

Using a 10% sample of the Australian national medicine dispensing claims data from 2022, we identified individuals aged 15-64 years with ≥2 antipsychotic dispensings (antipsychotic-users) and non-users. We extracted their past 5-year antipsychotic treatment patterns (dose, duration and use of multiple agents). Using Poisson re

SUBMITTER: Radha Krishnan RP 

PROVIDER: S-EPMC12925688 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature