The Effect of Midpregnancy Screening for Gestational Diabetes Mellitus on Pregnancy Outcomes: The TESGO Randomized Controlled Trial.

ABSTRACT:

Objective

Newborns delivered by women with gestational diabetes mellitus (GDM) have accelerated intrauterine growth earlier than the current recommended screening period. We aimed to determine whether universal GDM screening using a single oral glucose intolerance test (OGTT) at 18-20 weeks' gestation improves pregnancy outcomes compared with standard screening at 24-28 weeks' gestation.

Research design and methods

We conducted a dual-center, parallel, randomized controlled trial with a planned interim analysis in singleton pregnant women to compare the effect of midpregnancy screening for GDM at 18-20 weeks' gestation and standard screening at 24-28 weeks' gestation. GDM was universally screened and diagnosed using 75-g OGTTs and the International Association of the Diabete

SUBMITTER: Kuo CH 

PROVIDER: S-EPMC12925975 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature