Neuroeconomic adaptation to norm shifts is preserved in borderline personality disorder.

ABSTRACT:

Objective

Borderline personality disorder (BPD) is characterised by instability in interpersonal relationships, self-image, and affect. Dysregulated negative emotional processing involving prefrontal and limbic circuits is considered a neural basis of BPD. However, it remains unclear how prefrontal modulation of social decision-making in BPD differs from non-psychiatric controls.

Methods

To investigate social decision-making in response to unfairness, we conducted an functional magnetic resonance imaging study involving adults with a diagnosis of BPD (n = 77) and healthy controls (HCs; n = 60). Using an inequality aversion model, we derived parameters of social norm adaptation and inequality sensitivity from behavioural data during a modified ultimatum game des

SUBMITTER: Park I 

PROVIDER: S-EPMC12926737 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature