Sectoral and Layer-Specific Corneal Thinning in Thyroid Eye Disease: A Cross-Sectional Study.

ABSTRACT:

Purpose

Corneal thickness in patients with thyroid eye disease (TED) and the layer or specific region of the cornea primarily affected by corneal thickness changes remain unclear. This study aimed to examine and compare the differences in corneal thickness across various layers in patients with TED and a control group, focusing on identifying the specific corneal region where these changes are most pronounced.

Methods

This cross-sectional retrospective study included 57 eyes from 29 patients with TED and 18 eyes from 9 control participants. Basic eye examinations and corneal topography measurements were performed using a Galilei dual Scheimpflug camera and RTVue. Total corneal thickness, corneal epithelial thickness, and corneal stromal thickness (CST) were evaluated.

Res

SUBMITTER: Chang YM 

PROVIDER: S-EPMC12927423 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature