A Quantitative Printability Framework for Programmable Assembly of Pre-Vascular Patterns via Laser-Induced Forward Transfer.

ABSTRACT: The defined vascularization of complex and intricate tissue constructs remains an unmet need in tissue engineering and regenerative medicine. While large constructs require vasculature for oxygen, nutrient supply, and waste clearance, their incorporation within biofabricated tissues is essential for developmental and disease modeling studies. There is, therefore, a critical demand to establish reproducible and organized vascular networks within in vitro models to ensure experimental robustness and quantitative interpretability. Current micropatterning and biofabrication strategies are limited in emulating native geometrical complexity, throughput, and resolution, while self-assembly approaches rely on inherently random network formation. Here, laser-induced forward transfer (LIFT) is utili

SUBMITTER: Bosmans C 

PROVIDER: S-EPMC12927535 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature