Neighborhood Disadvantage and Recruitment and Retention of Participants in STRIDE, a Multi-Center Clinical Trial of Community-Living Older Persons.

ABSTRACT:

Background

Socioeconomically disadvantaged neighborhoods disproportionately include minority and poor populations that are often underrepresented in clinical trials. Our objective was to determine whether recruitment and retention of participants differ based on neighborhood disadvantage.

Methods

In a multi-center clinical trial that included 86 primary care practices within 10 US health care systems in 9 states, outreach to 140,850 patients led to enrollment of 5451 persons, 70 or older, at high risk for serious fall injuries. Multiple indicators of recruitment and retention were evaluated. Neighborhood disadvantage was defined as the highest quintile of scores on the state area deprivation index.

Results

Patients who lived in a disadvantaged neighborhood were less l

SUBMITTER: Gill TM 

PROVIDER: S-EPMC12927595 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature