Drug Reaction with Eosinophilia and Systemic Symptoms in the Electronic Medical Record.

ABSTRACT:

Introduction

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare severe cutaneous adverse reaction (AR), which can be life threatening [J Am Acad Dermatol. 2013;68(5):693.e1-14]. The reporting of DRESS in Australian electronic medical records (EMRs) has not been studied.

Methods

A dual ascertainment strategy was employed in this multi-centre, retrospective study. Part 1 involved data collection from a 2.5-year cohort of consecutive inpatient admissions. Patients with an AR label of DRESS, eosinophilia or severe rash were identified, along with the causative agents. Part 2 involved evaluating the AR label documentation for patients from an independently derived list of confirmed DRESS cases from an immunology department register. Case note review was under

SUBMITTER: Jiang M 

PROVIDER: S-EPMC12928710 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature