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Protective effects of Demethylfuropinnarin on porcine pre-implantation embryos under Tunicamycin-induced oxidative stress and endoplasmic reticulum stress during in vitro culture.


ABSTRACT:

SUBMITTER: Teng P 

PROVIDER: S-EPMC12929566 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature

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Protective effects of Demethylfuropinnarin on porcine pre-implantation embryos under Tunicamycin-induced oxidative stress and endoplasmic reticulum stress during in vitro culture.

Teng Peihong P   Yu Shaonan S   Yang Feiyang F   Zhang Ya-Nan YN   Liu Guifeng G   Li Chuang C  

Scientific reports 20260205 1


Assisted Reproductive Technologies (ART) are essential for addressing infertility and improving reproductive outcomes in both humans and animals. In vitro culture (IVC) supports embryo development outside the body but is often compromised by oxidative and endoplasmic reticulum (ER) stress, leading to impaired development and apoptosis. Demethylfuropinnarin (DMFP), a furocoumarin from Notopterygium incisum, has not been previously studied for its biological activity. Given the antioxidant propert  ...[more]

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