Stereotactic radioablation for ventricular tachycardia in patients untreatable by catheter ablation: evidence of efficacy, safety, and impact on coronary arteries.

ABSTRACT:

Aims

Ventricular tachycardia (VT) in patients with structural heart disease can be life-threatening and may persist despite anti-arrhythmic therapy and catheter ablation. When standard treatments are ineffective or contraindicated, stereotactic arrhythmia radioablation (STAR) has emerged as a non-invasive salvage option.

Methods and results

This prospective, single-centre study included 19 patients with structural heart disease and recurrent VT unresponsive to conventional therapy and who were ineligible for ablation. Patients were selected by a multidisciplinary team and underwent cardiac CT and electroanatomic mapping for substrate characterization. STAR was delivered in a single 25 Gy fraction using volumetric modulated arc therapy. Primary endpoints included safety (adve

SUBMITTER: Carbucicchio C 

PROVIDER: S-EPMC12929999 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature