Epidemiology and Outcomes of Sporotrichosis: A Descriptive Real-World Analysis From a Global Cohort.

ABSTRACT:

Background

Sporotrichosis is a dimorphic fungal infection of increasing global relevance. Although usually cutaneous or lymphocutaneous, disseminated disease occurs in immunocompromised hosts. Large-scale data on its epidemiology, treatment and outcomes remain limited.

Objectives

To characterise the clinical features, comorbidities, antifungal prescribing patterns and one-year mortality associated with sporotrichosis, with emphasis on patients with HIV and other forms of immunosuppression.

Patients/methods

We performed a retrospective global cohort study using the TriNetX Research Network. Adults (≥ 18 years) diagnosed with sporotrichosis were identified using ICD-9/10 codes (1995-2024). Demographics, comorbidities, laboratory parameters and antifungal prescriptions w

SUBMITTER: Schapiro S 

PROVIDER: S-EPMC12930329 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature